Dostie KE, Thees AV, Lynes MA. Metallothionein: A Novel Therapeutic Target for Treatment of Inflammatory Bowel Disease. Curr Pharm Des. 2018;24(27):3155-3161. doi: 10.2174/1381612824666180717110236.

Bhandari S, Melchiorre C, Dostie K, Laukens D, Devisscher L, Louwrier A, Thees A, Lynes MA. Detection and Manipulation of the Stress Response Protein Metallothionein. Curr Protoc Toxicol. 2017 Feb 1;71:17.19.1-17.19.28. doi: 10.1002/cptx.17. Review.

Dennis, K.K., Marder, M.E., Balshaw, D.M., Cui, Y., Lynes, M.A., Patti, G.J, Rappaport, S.M., Shaughnessy, D., Sosnoff, C., Vrijheid, M., Barr, D.B. (2016) Biomonitoring in the Era of the Exposome. Environmental Health Perspectives; DOI:10.1289/EHP474.

Rice, J.M., Zweifach, A., and Lynes, M.A. (2016) Metallothionein Regulates Intracellular Zinc Signaling during CD4+ T cell Activation. BMC Immunology; DOI: 10.1186/s12865-016-0151-2.

Emeny RE, Kasten-Jolly J,  Mondal T, Lynes MA, Lawrence DA (2015) Metallothionein differentially affects the host response to Listeria infection both with and without an additional stress from cold-restraint. Cell Stress and Chaperones. 20(6):1013-22 PMID: 26267326

Devisscher L, H.P., Lynes M, Waeytens A, Cuvelier C, De Vos F, Vanhove C, De Vos M, Laukens D.(2014) Role of metallothioneins as danger signals in the pathogenesis of colitis. J. Pathol 233:89-100 DOI: 10.1002/path.4330

Lynes MA, Hidalgo J, Manso Y, Devisscher L, Laukens D, Lawrence DA.(2014) Metallothionein and stress combine to affect multiple organ systems.Cell Stress Chaperones. 2014 Mar 2.

Yuk JS, Guignon EF, Lynes MA. Sensitivity enhancement of a grating-based surface plasmon-coupled emission (SPCE) bionsor chip using gold thickness. Chem Phys Lett. 2014 Jan 20;591:5-9.

Devisscher L, Hindryckx P, Lynes MA, Waeytens A, Cuvelier C, Vos FD, Vanhove C, Vos MD, Laukens(2014).  D.Role of metallothioneins as danger signals in the pathogenesis of colitis. J Pathol. 2014 Jan 22. doi: 10.1002/path.4330

Pietrosimone KM, Bhandari S, Lemieux MG, Knecht DA, Lynes MA.(2013) In vitro assays of chemotaxis as a window into mechanisms of toxicant-induced immunomodulation. Curr Protoc Toxicol. 2013 Nov 21;58:18.17.1-18.17.24. doi: 10.1002/0471140856.tx1817s58

Wanczyk H, Barker T, Rood D, Zapata DI, Howell AR, Richardson SK, Zinckgraf J, Marusov GP, Lynes MA, Silbart LK.(2013) Cloning and characterization of a hybridoma secreting a 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK)-specific monoclonal antibody and recombinant F(ab).Toxins (Basel). 2013 Mar 19;5(3):568-89. doi: 10.3390/toxins5030568.

Yuk JS, Guignon EF, Lynes MA. Highly sensitive grating coupler-based surface plasmon-coupled emission (SPCE) biosensor for immunoassay.(2013) Analyst. 2013 May 7;138(9):2576-82. doi: 10.1039/c3an00135k.

Molony RD, Rice JM, Yuk JS, Shetty V, Dey D, Lawrence DA, Lynes MA. (2012) Mining the salivary proteome with grating-coupled surface plasmon resonance imaging and surface plasmon coupled emission microarrays.  Curr Protoc Toxicol. 2012 Aug;Chapter 18:Unit 18.16.1-19. doi: 10.1002/0471140856.tx1816s53.

Yuk, J., Gibson, G., Rice, J., Guignon, E., and Lynes, M.A. (2012) Analysis of immunoarrays using a gold grating-based dual mode surface plasmon-coupled emission (SPCE) sensor chip, Analyst  (* co-first authors)  DOI: 10.1039/C2AN35143A.

Molony, R., Rice, J, Yuk, J., Shetty, V., Dey, D., Lawrence, D., Lynes, M.A. (2012) Mining the Salivary Proteome with Grating-Coupled Surface Plasmon Resonance Imaging and Surface Plasmon Coupled Emission Microarrays. Current Protocols in Toxicology (in press).

Pietrosimone, K. M., Yin, X., Knecht, D. A., Lynes, M. A. (2012) Measurement of Cellular Chemotaxis with ECIS/Taxis. J. Vis. Exp. (62), e3840, DOI: 10.3791/3840.

Rice, J.M., Stern, L.J., Guignon, E.F., Lawrence, D.A.,  and Lynes, M.A. (2012) T cell phenotyping microarrays using Grating Coupled Surface Plasmon Resonance Imaging and Surface Plasmon Coupled Emission. Biosensors and Bioelectronics, 31(1) 264-269 doi:10.1016/j.bios.2011.10.029 PMID: 22104646

Marusov, G.,  Sweatt, A., Guignon, E., Reilly, M.T., Geary, S.J., Silbart, L.K., Challa, S., Lagoy, J., and  Lynes, M.A. (2012) A Microarray Biosensor for Multiplexed Detection of Pathogens Using Grating-Coupled Surface Plasmon Resonance Imaging, Environmental Science and Technology, 2012, 46 (1), 348–359 DOI: 10.1021/es201239f  PMID: 22029256

Lynes, MA (2010) Immunomodulation by toxicant-induced stress proteins. In Comprehensive Toxicology, (2nd edition) D. A. Lawrence, editor.  Elsevier Press, NY.

Lynes, M.A. (2010) Molecular and cellular concepts in toxicology.  in General and Applied Toxicology, Third edition. Ballantyne, B., Marrs, T., and Syversen, T. (eds.) John Wiley and Sons Ltd, Chichester, UK pp 229-245.

Lynes, M.A., Pietrosimone, K. , Marusov, G †, Donaldson, D.V., Tarracciano, C., Yin, X., Lawrence, D.A., and McCabe, M.J. (2010) “Metal influences on immune function” In: Cellular and Molecular Biology of Metals. J. Koropatnick and R. Zalups, editors, Taylor and Francis Publishers, London and New York.

Emeny, R.T*. , Marusov, G.* , Lawrence,D.A., Pederson-Lane, J., Yin, X. , and Lynes, M.A. (2009) Manipulations of metallothionein gene dose accelerate the response to Listeria monocytogenes. Chemico-Biological Interactions (2009),181: 243-253 doi:10.1016/j.cbi.2009.06.018. (* co-first authors)

Lynes, M.A., Canpolat†, E., Crowthers†, K.C., Unfricht†, D.W., Pilar**, G., Marusov†, G., Silbart, L.K., and Yin††, X. (2008) Metal-mediated immunomodulation; a role for metallothionein in both normal and stressed immune systems in Metal Ions in Biology and Medicine, v10. Eds. Collery, P., Threophanides, T., Khassanova, L., and Collery, T. John Libbey Eurotext , Paris p. 561-568.

Lynes, M.A., Kang, Y.J., Sensi, S.L., Perdrizet, G.A., and Hightower, L.E. (2007) Heavy Metal ions in normal physiology, toxic stress and cytoprotection.  Ann. NY Acad Sci. 1113:159-172.

Hadjout, N., X. †, Yin††, D. A. Knecht, and M. A. Lynes. (2007). Automated real-time measurements of leukocyte chemotaxis. J Immunol Methods. 2007 320(1-2):70-80

Lynes, M.A., Zaffuto, K., Unfricht, D.W., Marusov, G., Samson, J.S., and Yin, X (2006) The physiological roles of extracellular metallothionein. Journal of Experimental Biology and Medicine. 231:1548-1554.

Lynes and Yin (2006) Metallothionein and anti-metallothionein, complementary elements of cadmium-induced renal disease. Tox Sci. 91: 1 – 3.

Jin, G-B,  Unfricht, D.W., Fernandez, S.M., and Lynes, M.A. (2006) Cytometry on a Chip: Cellular phenotype and functional analysis using grating-coupled surface plasmon resonance. Biosensors and Bioelectronics. 22:200-206.

Reilly Sr., M.T., Nessing, P.A., Guignon, E.F. , Lynes, M.A. , Fernandez, S.M. (2006) SPR surface enhanced fluorescence with a gold-coated corrugated sensor chip Progress in Biomedical Optics and Imaging – Proceedings of SPIE Volume 6099, 2006, Article number 60990E  DOI: 10.1117/12.646165

Lynes, M.A., Fontenot, A.P., Lawrence, D.A., Rosenspire, A,J., and Pollard, K.M.. (2006) Gene Effects on metal-mediated immunomodulation” Toxicology and Applied Pharmacology 210:9-16.

Yin, X., Knecht,, D.A., and Lynes, M.A. (2005) Metallothionein mediates leukocyte chemotaxis. BMC Immunology 6:21-33.  This article is listed at “highly accessed” by BMC Immunology, and stands 5th in the number of accesses for 2005/2006.

Unfricht,D.W., Colpitts, S.L, Fernandez,S.M., and Lynes, M.A. (2005) Grating-coupled surface plasmon resonance: a cell and protein microarray  platform, Proteomics, Published Online: 13 Oct 2005. 5(17): p. 4432-4442.

Lynes, M.A. (2004) Solid Phase Immunoassays.  In Current Protocols in Toxicology. Maines, M.D., Costa, L.G., Hodgson, E.,  Lawerence, D.A., Oxolins ,T.R., and Reed, D.J.(eds.) John Wiley & Sons, Inc.

B.L. Lyons, M.A. Lynes, N. Hadjout, M. J. Joliat, D. A. Lawrence, M. Barber and L.D. Shultz “The Origins of Anemia in Autoimmune Viable Motheaten Mice” (2003) Exp. Hematol.31: 234-243.

Zieziulewicz, T.J., D. W. Unfricht, N. Hadjout, M. A. Lynes, and D.A. Lawrence 2003 “Shrinking the biologic world: nanobiotechnologies for toxicology” Tox. Sci. 2003 74: 235-244.

Joliat, M.J., Umeda, S., Lyons, B.L., Lynes, M.A., and Shultz, L.D. (2002) Establishment and characterization of a new osteogenic cell line (MOS-J) from a spontaneous C57BL/6J mouse ostosarcoma. In vivo 16:223-228.

Youn, J., Hwang, S.-H., Ryoo, Z.-Y., Lynes, M.A., Paik, D.J., Chung, H.S., and Kim, H.-Y. (2002) Metallothionein suppresses collagen-induced arthritis via induction of TGF-b and downregulation of proinflammatory mediators,  Clin Exp Immunol,129: 232-239.

Joliat,M.J., P.A. Lang  , B.L. Lyons , L. Burzenski  ,M.A. Lynes  , T. Yi  , J.P. Sundberg and L.D. Shultz (2002) Absence of CD5 dramatically reduces progression of pulmonary inflammatory lesions in SHP-1 protein-tyrosine phosphatase-deficient viable motheaten mice. J. Autoimmunity. 18:105-117.